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Pressure tracing recorded in a patient with an isolated stenosis in the mid left anterior descending coronary artery. A, Central aortic pressure (Pao) recorded through the guide catheter and distal coronary pressure (Pc) recorded through a high-fidelity 0.018-in pressure monitoring guide wire are measured under baseline conditions. Mean translesional pressure gradient (ΔPrest) is 9 mm Hg. Pfem indicates pressure in the femoral artery.